久草精品视频在线播放,中文人妻AV久久人妻水密桃,av免费观看精品,亚洲五月激情综合图片区 日本成熟少妇A∨网站,久久看亚洲欧美,久久久久久人妻精品一区,久久亚洲Aⅴ无码影院

產品中心

Dematin rabbit pAb
一鍵復制產品信息
ES2161
規(guī)格： 價格：
50μL ￥1280.00
100μL ￥1980.00

Overview

Product name: Dematin rabbit pAb
Reactivity: Human;Mouse
Alternative Names: EPB49; DMT; Dematin; Erythrocyte membrane protein band 4.9
Source: Rabbit
Dilutions: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human Dematin. AA range:356-405
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 50kD
GeneID: 2039
Human Swiss-Prot No: Q08495
Cellular localization: Cytoplasm. Cytoplasm, cytosol. Cytoplasm, perinuclear region . Cytoplasm, cytoskeleton. Cell membrane. Membrane . Endomembrane system. Cell projection . Localized at the spectrin-actin junction of erythrocyte plasma membrane. Localized to intracellular membranes and the cytoskeletal network. Localized at intracellular membrane-bounded organelle compartment in platelets that likely represent the dense tubular network membrane. Detected at the cell membrane and at the parasitophorous vacuole in malaria-infected erythrocytes at late stages of plasmodium berghei or falciparum development.
Background: The protein encoded by this gene is an actin binding and bundling protein that plays a structural role in erythrocytes, by stabilizing and attaching the spectrin/actin cytoskeleton to the erythrocyte membrane in a phosphorylation-dependent manner. This protein contains a core domain in the N-terminus, and a headpiece domain in the C-terminus that binds F-actin. When purified from erythrocytes, this protein exists as a trimer composed of two 48 kDa polypeptides and a 52 kDa polypeptide. The different subunits arise from alternative splicing in the 3' coding region, where the headpiece domain is located. Disruption of this gene has been correlated with the autosomal dominant Marie Unna hereditary hypotrichosis disease, while loss of heterozygosity of this gene is thought to play a role in prostate cancer progression. Alternative splicing results in multiple transcript variants encoding di
關閉

在線咨詢

Online consultation

  • 在線咨詢
  • 技術支持

關注微信公眾號

微信掃一掃立即咨詢

微信掃一掃立即咨詢

關閉