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產(chǎn)品中心

CYP2C19 rabbit pAb

一鍵復制產(chǎn)品信息

ES2100

規(guī)格：	價格：
50μL	￥1280.00
100μL	￥1980.00

下載說明 ①

Overview

Product name:	CYP2C19 rabbit pAb
Reactivity:	Human;Rat;Mouse;
Alternative Names:	CYP2C19; Cytochrome P450 2C19; (R)-limonene 6-monooxygenase; (S)-limonene 6-monooxygenase; (S)-limonene 7-monooxygenase; CYPIIC17; CYPIIC19; Cytochrome P450-11A; Cytochrome P450-254C; Mephenytoin 4-hydroxylase
Source:	Rabbit
Dilutions:	Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications.
Immunogen:	The antiserum was produced against synthesized peptide derived from human Cytochrome P450 2C19. AA range:241-290
Storage:	-20°C/1 year
Clonality:	Polyclonal
Isotype:	IgG
Concentration:	1 mg/ml
Observed Band:	56kD
GeneID:	1557
Human Swiss-Prot No:	P33261
Cellular localization:	Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
Background:	cytochrome P450 family 2 subfamily C member 19(CYP2C19) Homo sapiens This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is known to metabolize many xenobiotics, including the anticonvulsive drug mephenytoin, omeprazole, diazepam and some barbiturates. Polymorphism within this gene is associated with variable ability to metabolize mephenytoin, known as the poor metabolizer and extensive metabolizer phenotypes. The gene is located within a cluster of cytochrome P450 genes on chromosome 10q24. [provided by RefSeq, Jul 2008],

Western Blot analysis of various cells using CYP2C19 Polyclonal Antibody diluted at 1:1000
Western Blot analysis of MOUSE-BRAIN cells using CYP2C19 Polyclonal Antibody diluted at 1:1000
Western blot analysis of lysates from 293 cells, using Cytochrome P450 2C19 Antibody. The lane on the right is blocked with the synthesized peptide.
Immunohistochemical analysis of paraffin-embedded human Gastric adenocarcinoma. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).

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