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AMPKα1/2 rabbit pAb
一鍵復(fù)制產(chǎn)品信息
ES1649
規(guī)格： 價格：
50μL ￥1280.00
100μL ￥1980.00

Overview

Product name: AMPKα1/2 rabbit pAb
Reactivity: Human;Mouse;Rat;Monkey;Bovine
Alternative Names: PRKAA1; AMPK1; 5'-AMP-activated protein kinase catalytic subunit alpha-1; AMPK subunit alpha-1; Acetyl-CoA carboxylase kinase; ACACA kinase; Hydroxymethylglutaryl-CoA reductase kinase; HMGCR kinase; Tau-protein kinase PRKAA1; PRKAA2; AMPK;
Source: Rabbit
Dilutions: WB 1:500-2000;IHC-p 1:100-500;IF/ICC 1:100-500;ELISA 1:5000-20000
Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha. AA range:140-189
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 63kD
GeneID: 5562/5563
Human Swiss-Prot No: Q13131/P54646
Cellular localization: Cytoplasm . Nucleus . In response to stress, recruited by p53/TP53 to specific promoters. .
Background: The protein encoded by this gene belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008],
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