久草精品视频在线播放,中文人妻AV久久人妻水密桃,av免费观看精品,亚洲五月激情综合图片区 日本成熟少妇A∨网站,久久看亚洲欧美,久久久久久人妻精品一区,久久亚洲Aⅴ无码影院

產(chǎn)品中心

YAP (phospho Ser127) rabbit pAb
一鍵復(fù)制產(chǎn)品信息
ES1489
規(guī)格: 價(jià)格:
50μL ¥1280.00
100μL ¥1980.00

Overview

Product name: YAP (phospho Ser127) rabbit pAb
Reactivity: Human;Mouse;Rat;Monkey
Alternative Names: YAP1; YAP65; Yorkie homolog; 65 kDa Yes-associated protein; YAP65
Source: Rabbit
Dilutions: IF: 1:50-200 Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human YAP around the phosphorylation site of Ser127. AA range:93-142
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 65kD
GeneID: 10413
Human Swiss-Prot No: P46937
Cellular localization: Cytoplasm . Nucleus . Both phosphorylation and cell density can regulate its subcellular localization (PubMed:18158288, PubMed:20048001). Phosphorylation sequesters it in the cytoplasm by inhibiting its translocation into the nucleus (PubMed:18158288, PubMed:20048001). At low density, predominantly nuclear and is translocated to the cytoplasm at high density (PubMed:18158288, PubMed:20048001, PubMed:25849865). PTPN14 induces translocation from the nucleus to the cytoplasm (PubMed:22525271). Localized mainly to the nucleus in the early stages of embryo development with expression becoming evident in the cytoplasm at the blastocyst and epiblast stages (By similarity). .
Background: This gene encodes a downstream nuclear effector of the Hippo signaling pathway which is involved in development, growth, repair, and homeostasis. This gene is known to play a role in the development and progression of multiple cancers as a transcriptional regulator of this signaling pathway and may function as a potential target for cancer treatment. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2013],
關(guān)閉

在線咨詢

Online consultation

  • 在線咨詢
  • 技術(shù)支持

關(guān)注微信公眾號

微信掃一掃立即咨詢

微信掃一掃立即咨詢

關(guān)閉