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Cleaved-PARP-1 (D214) rabbit pAb
一鍵復(fù)制產(chǎn)品信息
ES1071
規(guī)格： 價格：
50μL ￥1280.00
100μL ￥1980.00

Overview

Product name: Cleaved-PARP-1 (D214) rabbit pAb
Reactivity: Human;Mouse
Alternative Names: PARP1; ADPRT; PPOL; Poly [ADP-ribose] polymerase 1; PARP-1; ADP-ribosyltransferase diphtheria toxin-like 1; ARTD1; NAD(+) ADP-ribosyltransferase 1; ADPRT 1; Poly[ADP-ribose] synthase 1
Source: Rabbit
Dilutions: WB 1:500-2000, IF 1:50-300, IHC 1:50-300
Immunogen: The antiserum was produced against synthesized peptide derived from human PARP. AA range:165-214
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 24kD
GeneID: 142
Human Swiss-Prot No: P09874
Cellular localization: Nucleus . Nucleus, nucleolus . Chromosome . Localizes to sites of DNA damage. .
Background: This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes. [provided by RefSeq, Jul 2008],
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