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產(chǎn)品中心

FH/Fumarase Mouse mAb

一鍵復(fù)制產(chǎn)品信息

EM1073

規(guī)格：	價格：
50μL	￥1280.00
100μL	￥1980.00

下載說明 ①

Overview

Product name:	FH/Fumarase Mouse mAb
Reactivity:	Human, Rat, Mouse
Alternative Names:	Fumarase, fumarate hydratase, HLRCC, LRCC, MCL, MCUL1
Source:	Mouse
Dilutions:	WB 1:3,000 IF 1:100-200
Immunogen:	Synthetic Peptide
Storage:	PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid?repeated?freeze-thaw?cycles.
Clonality:	Monoclonal
Isotype:	IgG1
Concentration:	1mg/mL
Observed Band:	50kDa
GeneID:	2271
Human Swiss-Prot No:	P07954
Cellular localization:	Cytoplasm and Mitochondrion.
Background:	Fumarase (FH) is an enzyme that catalyzes the reversible hydration/dehydration of fumarate to malate. Fumarase comes in two forms: mitochondrial and cytosolic. The mitochondrial isoenzyme is involved in the Krebs Cycle (also known as the Tricarboxylic Acid Cycle [TCA] or the Citric Acid Cycle), and the cytosolic isoenzyme is involved in the metabolism of amino acids and fumarate. Subcellular localization is established by the presence of a signal sequence on the amino terminus in the mitochondrial form, while subcellular localization in the cytosolic form is established by the absence of the signal sequence found in the mitochondrial variety.

Western blot analysis of 1) 293T, 2) HepG2, 3) Hela, with FH Mouse mAb diluted at 1:3,000.
Western blot analysis of 1) Mouse Brain tissue, 2) Rat Brain tissue, with FH Mouse mAb diluted at 1:3,000.
IF analysis of Hela with EM1073 diluted at 1:100.

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