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Kininogen 1 Rabbit pAb
一鍵復(fù)制產(chǎn)品信息
EA367
規(guī)格： 價格：
50μL ￥1280.00
100μL ￥1980.00

Overview

Product name: Kininogen 1 Rabbit pAb
Reactivity: Human, Mouse, Rat
Alternative Names: BDK, Fitzgerald factor, HMWK, Ile Ser Bradykinin Bradykinin, Kallidin I Lysyl bradykinin, kininogen 1, KNG, KNG1
Source: Rabbit
Dilutions: WB 1:1500-1,000? IHC 1:100-200
Immunogen: Recombinant Protein
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid?repeated?freeze-thaw?cycles.
Clonality: Polyclonal
Isotype: IgG
Concentration: 1mg/mL
Observed Band: 45-120kDa
GeneID: 3827
Human Swiss-Prot No: P01042
Cellular localization: Secreted
Background: Kininogens are inhibitors of thiol proteases; ?HMW-kininogen plays an important role in blood coagulation by helping to position optimally prekallikrein and factor XI next to factor XII; HMW-kininogen inhibits the thrombin- and plasmin-induced aggregation of thrombocytes; ?the active peptide bradykinin that is released from HMW-kininogen shows a variety of physiological effects. LMW-kininogen inhibits the aggregation of thrombocytes; ?LMW-kininogen is in contrast to HMW-kininogen not involved in blood clottingUCHL1, UCHL3, UCHL5/UCH37, and BRCA-1-associated protein-1 (BAP1) belong to the UCH family of DUBs, which all posses a conserved catalytic domain (UCH domain) of about 230 amino acids.??UCHL1 is abundantly expressed in neuronal tissues and testes.
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